I've noticed that there is a connection between the image of the eye and physical death.
1. There are images of eyes found in the Catacombs and the Underworld, both of which are areas inhabited by the dead.
2. The Eye of Janthir is used to select those "Chosen" who will be sacrificed to power the Bloodstones.
3. Abaddonian lore includes several references to the eating of eyes by Abaddon and his minions,, and eyes can be found (in physical form, as opposed to artisticly) throughout the Realm of Torment.
While I am not going to get into the discussion concerning the pictographic resemblence between the Catacombs/Underworld and Janthir portrayals, I do find it interesting that the eyes all have to do with death in some form.
An old saying states that the "eyes are the window to a person's soul". Could the depictions of eyes have to do with a person's soul, either with their passage to another realm (Catacombs/UW) or marking for a purpose (Janthir/Chosen and Abaddon/cursed)?